概述

  • 产品名称
    Anti-PDGF AB + BB抗体
  • 描述
    山羊多克隆抗体to PDGF AB + BB
  • 宿主
    Goat
  • 经测试应用
    适用于: WB, Neutralisingmore details
  • 种属反应性
    与反应: Mouse, Rat, Cow, Human, Pig
  • 免疫原

    Purified human PDGF-AB

  • 阳性对照
    • 3T3 cells

性能

应用

Our Abpromise guarantee covers the use of ab34074 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
Neutralising
  • 应用说明
    Neut: Use at a concentration of 10 - 20 µg/ml. In a 5 day assay, 10-20ug/ml inhibited 3T3 cell growth by 60-75% as stimulated by 10ng/ml of PDGF-AB.
    WB: Use at a concentration of 5 - 10 µg/ml. Predicted molecular weight: 124 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性
      Platelet-Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis.
    • 细胞定位
      Secreted
    • 数据库链接
    • 别名
      • Becaplermin antibody
      • c sis antibody
      • FLJ1285 antibody
      • Oncogene SIS antibody
      • PDGF 1 antibody
      • PDGF 2 antibody
      • PDGF A antibody
      • PDGF A chain antibody
      • PDGF B chain antibody
      • PDGF subunit A antibody
      • PDGF subunit B antibody
      • PDGF1 antibody
      • PDGF2 antibody
      • PDGFA antibody
      • PDGFB antibody
      • Platelet derived growth factor 2 antibody
      • Platelet derived growth factor alpha antibody
      • Platelet derived growth factor alpha chain antibody
      • Platelet derived growth factor alpha polypeptide antibody
      • Platelet derived growth factor B chain antibody
      • Platelet derived growth factor beta antibody
      • Platelet derived growth factor beta polypeptide antibody
      • Platelet derived growth factor subunit A antibody
      • Platelet derived growth factor subunit B antibody
      • SIS antibody
      • SSV antibody
      • v sis platelet derived growth factor beta polypeptide antibody
      see all

    实验方案

    文献

    This product has been referenced in:
    • Chen XW  et al. CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis. Oncogene N/A:N/A (2017). Mouse . Read more (PubMed: 28481877) »
    • Song CH  et al. Identification of chemoattractive factors involved in the migration of bone marrow-derived mesenchymal stem cells to brain lesions caused by prions. J Virol 85:11069-78 (2011). Read more (PubMed: 21813601) »

    See all 2 Publications for this product

    客户评价及客户问答

    This PDGF antibody was raised against purified PDGF from human platelets.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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