概述

  • 产品名称Anti-PDGF AA抗体
    参阅全部 PDGF AA 一抗
  • 描述
    兔多克隆抗体to PDGF AA
  • 经测试应用适用于: WB, IP, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Fusion protein corresponding to Human PDGF AA aa 1-196. A fusion recombinant protein derived from E coli.
    Database link: P04085-2

  • 阳性对照
    • PDGF-proprietary tag recombinant fusion protein; Mouse embryo tissue and LS174T lysates.

性能

应用

Our Abpromise guarantee covers the use of ab125268 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 1 µg/ml. Detects a band of approximately 23 kDa (predicted molecular weight: 24 kDa).
IP Use a concentration of 2 - 5 µg/ml.
ELISA Use a concentration of 0.01 - 0.1 µg/ml.
IHC-P Use a concentration of 2 - 5 µg/ml.

靶标

  • 功能Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
  • 序列相似性Belongs to the PDGF/VEGF growth factor family.
  • 结构域The long form contains a basic insert which acts as a cell retention signal.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • PDGF A antibody
    • PDGF A chain antibody
    • PDGF subunit A antibody
    • PDGF-1 antibody
    • PDGF1 antibody
    • PDGFA antibody
    • PDGFA_HUMAN antibody
    • Platelet derived growth factor alpha chain antibody
    • Platelet derived growth factor alpha isoform 2 preproprotein antibody
    • Platelet derived growth factor alpha polypeptide antibody
    • Platelet-derived growth factor A chain antibody
    • Platelet-derived growth factor alpha polypeptide antibody
    • Platelet-derived growth factor subunit A antibody
    see all

Anti-PDGF AA antibody 图像

  • All lanes : Anti-PDGF AA antibody (ab125268) at 1/500 dilution

    Lane 1 : Recombinant protein PDGF-proprietary tag
    Lane 2 : Mouse embryo tissue
    Lane 3 : LS174T


    Predicted band size : 24 kDa
    Resolved on 12% SDS-PAGE. An immunoreactive protein at ~50 kDa (PDGF-proprietary tag fusion protein) or 23 kDa was observed.

Anti-PDGF AA antibody (ab125268)参考文献

This product has been referenced in:
  • Duran JM  et al. Bone-derived stem cells repair the heart after myocardial infarction through transdifferentiation and paracrine signaling mechanisms. Circ Res 113:539-52 (2013). WB ; Mouse . Read more (PubMed: 23801066) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"