Anti-PDE9A抗体(ab125672)

概述

  • 产品名称Anti-PDE9A抗体
    参阅全部 PDE9A 一抗
  • 描述
    兔多克隆抗体to PDE9A
  • 经测试应用适用于: WB, IHC-P, IPmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide, corresponding to amino acids at the C-terminal of Human PDE9A.

  • 阳性对照
    • Insect cells transfected with Human PDE9A.

性能

应用

Our Abpromise guarantee covers the use of ab125672 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000 - 1/5000. Predicted molecular weight: 68 kDa.
IHC-P Use at an assay dependent concentration.
IP Use at an assay dependent concentration.

靶标

  • 功能Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.
  • 组织特异性Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate.
  • 序列相似性Belongs to the cyclic nucleotide phosphodiesterase family. PDE9 subfamily.
  • 结构域Composed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.
  • 细胞定位Cytoplasm. Endoplasmic reticulum; Cell projection > ruffle membrane. Cytoplasm > perinuclear region and Cell projection > ruffle membrane. Cytoplasm > perinuclear region. Golgi apparatus. Endoplasmic reticulum.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5''-cyclic phosphodiesterase 9A antibody
    • cGMP specific 3' 5' cyclic phosphodiesterase type 9 antibody
    • FLJ90181 antibody
    • High affinity cGMP-specific 3'' antibody
    • High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A antibody
    • HSPDE9A2 antibody
    • OTTHUMP00000109399 antibody
    • PDE 9A antibody
    • Pde9a antibody
    • PDE9A_HUMAN antibody
    • Phosphodiesterase 9A antibody
    • phosphodiesterase PDE9A21 antibody
    see all

Anti-PDE9A antibody 图像

  • All lanes : Anti-PDE9A antibody (ab125672) at 1/2000 dilution

    Lane 1 : Insect cells, transfected with Human PDE1A3
    Lane 2 : Insect cells transfected with Human PDE2A3
    Lane 3 : Insect cells, transfected with Human PDE3A
    Lane 4 : Insect cells, transfected with Human PDE4A1
    Lane 5 : Insect cells, transfected with Human PDE5A2
    Lane 6 : Insect cells, transfected with Human PDE7A
    Lane 7 : Insect cells, transfected with Human PDE8A1
    Lane 8 : Insect cells, transfected with Human PDE8B
    Lane 9 : Insect cells transfected with Human PDE9A2
    Lane 10 : Insect cells, transfected with Human PDE10A1
    Lane 11 : Insect cells, transfected with Human PDE11A1

    Developed using the ECL technique

    Predicted band size : 68 kDa

Anti-PDE9A antibody (ab125672)参考文献

ab125672 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Brain)
Permeabilization Yes - Triton X-100
Specification Brain
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
Fixative Paraformaldehyde
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提交于 Jul 11 2016

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