概述

  • 产品名称
  • 描述
    兔多克隆抗体to PDE8A
  • 经测试应用
    适用于: WB, IPmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic cyclic peptide, corresponding to the mid region of PDE8A.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab14619 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IP
  • 应用说明
    IP: 1/250.
    WB: 1/500. Detects a band of approximately 98-102 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
    • 组织特异性
      Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.
    • 通路
      Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
    • 序列相似性
      Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
      Contains 1 PAC (PAS-associated C-terminal) domain.
      Contains 1 PAS (PER-ARNT-SIM) domain.
    • 结构域
      Composed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 5''-cyclic phosphodiesterase 8A antibody
      • cAMP specific cyclic nucleotide phosphodiesterase 8A antibody
      • FLJ16150 antibody
      • High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A antibody
      • High affinity cAMP-specific and IBMX-insensitive 3'' antibody
      • HsT19550 antibody
      • PDE 8A antibody
      • PDE8A antibody
      • PDE8A_HUMAN antibody
      • Phosphodiesterase 8A antibody
      • Phosphodiesterase8A antibody
      • Weakly similar to 3'5' cyclic nucleotide phosphodiesterase antibody
      see all

    Anti-PDE8A antibody (ab14619)参考文献

    This product has been referenced in:
    • Kelly MP  et al. Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. Cell Signal 26:383-397 (2013). Mouse, Rat . Read more (PubMed: 24184653) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab14619.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    注册