概述

  • 产品名称PDE6 gamma肽

描述

  • 性质Synthetic

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技术指标

Our Abpromise guarantee covers the use of ab5864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • 补充说明


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human PDE6 gamma, catalog ab5664. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • 5''-cyclic phosphodiesterase subunit gamma
    • CNRG_HUMAN
    • GMP-PDE gamma
    • MGC125749
    • PDE 6
    • PDE6G
    • PDEG
    • Phosphodiesterase 6G cGMP Specific
    • Phosphodiesterase 6G cGMP specific rog gamma
    • Retinal Rod Photoreceptor cGMP Phosphodiesterase gamma
    • Retinal rod rhodopsin sensitive cGMP 3' 5'vcyclic phosphodiesterase subunit gamma
    • Retinal rod rhodopsin-sensitive cGMP 3''
    • Rod cG PDE G
    • RP57
    see all
  • 功能Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
  • 疾病相关Defects in PDE6G are the cause of retinitis pigmentosa type 57 (RP57) [MIM:613582]. RP57 is a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • 序列相似性Belongs to the rod/cone cGMP-PDE gamma subunit family.
  • Information by UniProt

PDE6 gamma peptide (ab5864)参考文献

ab5864 has not yet been referenced specifically in any publications.

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