Anti-PDE4C抗体(ab14608)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to PDE4C
  • 特异性
    This antibody detects 3 isoforms of PDE4C subclasses (PDE4C1, PDE4C2 and PDE4C3).
  • 经测试应用
    适用于: IP, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic cyclic peptide (carboxy-terminal peptide common to all PDE4C proteins).

  • 阳性对照
    • recombinant protein PDE4C1/2

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Thimerosal / Merthiolate
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab14608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP 1/20.
WB 1/500. Predicted molecular weight: 80 kDa.Can be blocked with PDE4C peptide (ab169990).

靶标

  • 功能
    Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
  • 组织特异性
    Expressed in various tissues but not in cells of the immune system.
  • 通路
    Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
  • 序列相似性
    Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5''-cyclic phosphodiesterase 4C antibody
    • cAMP specific 3' 5' cyclic phosphodiesterase 4C antibody
    • cAMP-specific 3'' antibody
    • DPDE 1 antibody
    • DPDE1 antibody
    • MGC126222 antibody
    • PDE 21 antibody
    • PDE 4C antibody
    • PDE21 antibody
    • Pde4c antibody
    • PDE4C_HUMAN antibody
    • Phosphodiesterase 4C antibody
    • Phosphodiesterase 4C cAMP specific antibody
    • Phosphodiesterase 4C, cAMP specific (phosphodiesterase E1 dunce homolog, Drosophila) antibody
    • Phosphodiesterase E1 dunce homolog antibody
    • Phosphodiesterase E1 dunce homolog Drosophila antibody
    • Phosphodiesterase type 4C antibody
    see all

Anti-PDE4C antibody (ab14608)参考文献

ab14608 has not yet been referenced specifically in any publications.

Product Wall

Application
Western blot
Sample
Rat Cell lysate - whole cell (Astrocytes)
Loading amount
40 µg
Specification
Astrocytes
Gel Running Conditions
Reduced Denaturing (12)
Blocking step
BSA as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Username

Abcam user community

Verified customer

提交于 Jan 24 2013

Thank you for your enquiry. 1) PDE4A antibody (ab14607) does not cross react to any known PDE4 subtype except all the PDE4A subtype variants including PDE4A1, A5, Ax, A8, it has little or no reactivity towards PDE4A10 and PDE4A11. We have tested fo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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