Anti-PDE4B抗体(ab112014)

概述

  • 产品名称Anti-PDE4B抗体
    参阅全部 PDE4B 一抗
  • 描述
    山羊多克隆抗体to PDE4B
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide:

    C-DIDIATEDKSPVDT

    , corresponding to C terminal amino acids 723-736 of Human PDE4B.

  • 阳性对照
    • Human prostate tissue; Mouse brain lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab112014 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 83 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
  • 组织特异性Expressed in brain, heart, lung and skeletal muscle.
  • 通路Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
  • 序列相似性Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5''-cyclic phosphodiesterase 4B antibody
    • cAMP-specific 3'' antibody
    • cAMP-specific 3',5'-cyclic phosphodiesterase 4B antibody
    • cAMP-specific phosphodiesterase-4 B isoform antibody
    • DKFZp686F2182 antibody
    • DPDE4 antibody
    • dunce-like phosphodiesterase E4 antibody
    • MGC126529 antibody
    • OTTHUMP00000010652 antibody
    • OTTHUMP00000010653 antibody
    • OTTHUMP00000010654 antibody
    • OTTHUMP00000010656 antibody
    • OTTHUMP00000232365 antibody
    • PDE 4B antibody
    • PDE IVB antibody
    • PDE32 antibody
    • Pde4b antibody
    • PDE4B_HUMAN antibody
    • PDE4B5 antibody
    • PDEIVB antibody
    • Phosphodiesterase 4B antibody
    • Phosphodiesterase 4B cAMP specific antibody
    • Phosphodiesterase 4B, cAMP specific (phosphodiesterase E4 dunce homolog, Drosophila) antibody
    see all

Anti-PDE4B antibody 图像

  • ab112014, at 5µg/ml, staining PDE4B in formalin-fixed, paraffin-embedded Human Prostate tissue by Immunohistochemistry.
  • Anti-PDE4B antibody (ab112014) at 0.5 µg/ml + Mouse Brain lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 83 kDa

Anti-PDE4B antibody (ab112014)参考文献

ab112014 has not yet been referenced specifically in any publications.

Product Wall


Have you considered using a postive control: like a mouse brain lysate (ab7188)or prostate tissue (ab30304) to see if it works. This antibody has been tested on these tissue and is known to work. Since you are unsure of the expression in your wt s...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"