Anti-PDE3B抗体[SMCP3B] (ab95814)
Key features and details
- Rat monoclonal [SMCP3B] to PDE3B
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG2a
概述
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产品名称
Anti-PDE3B抗体[SMCP3B]
参阅全部 PDE3B 一抗 -
描述
大鼠单克隆抗体[SMCP3B] to PDE3B -
宿主
Rat -
特异性
ab95814 is specific to PDE3B. It does not react with PDE3A. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse
不与反应: Human -
免疫原
Recombinant fragment, corresponding to C terminal amino acids 643-1100 of Mouse PDE3B expressed in E. coli.
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阳性对照
- Mouse heart lysate; Mouse lymph node cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: 2.68% PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
SMCP3B -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab95814于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 124 kDa.
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说明 |
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WB
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 124 kDa. |
靶标
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功能
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. -
组织特异性
Abundant in adipose tissues. -
序列相似性
Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 18576 Mouse
- SwissProt: Q61409 Mouse
- Unigene: 430730 Mouse
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别名
- 5''-cyclic phosphodiesterase B antibody
- Adipocyte cAMP phosphodiesterase cGMP inhibited antibody
- AI847709 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (1)
ab95814 被引用在 1 文献中.
- Vang AG et al. Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac. Biochem J 456:463-73 (2013). PubMed: 24007532