This antibody has no cross reactivity against PDE2B or with other PDE family members tested so far.
Mouse, Rat, Human
, corresponding to C terminal amino acids 897-914 of Mouse PDE2A
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500. Detects a band of approximately 95-97 kDa in samples from rat brain.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.
Contains 2 GAF domains.
GAF 1 functions as a dimerization domain, whereas GAF 2 binds cGMP, which causes activation of the catalytic activity of the enzyme.
Information by UniProt
- 5''-cyclic phosphodiesterase antibody
- cGMP dependent 3'5' cyclic phosphodiesterase antibody
- cGMP stimulated phosphodiesterase 1 antibody
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