Mouse, Rat, Cow, Dog
Recombinant fragment corresponding to a region within amino acids 212-520 of Human PDE1A (NP_001003683).
EB: H1299 and HeLa whole cell lysates; 293T, A431, H1299, HepG2, MOLT4 and Raji cell lysates
ICC/If: HeLa cell
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 61 kDa.
1/100 - 1/200.
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
Several tissues, including brain, kidney, testes and heart.
Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
Information by UniProt
3' 5' cyclic nucleotide phosphodiesterase antibody
5''-cyclic nucleotide phosphodiesterase 1A antibody
61 kDa Cam PDE antibody
Anti-PDE1A antibody 图像
Western blot - PDE1A antibody (ab96336)
All lanes : Anti-PDE1A antibody (ab96336) at 1/1000 dilution Lane 1 : H1299 whole cell lysate Lane 2 : HeLa whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size : 61 kDa
Immunocytochemistry/ Immunofluorescence - PDE1A antibody (ab96336)
ab96336, at a 1/200 dilution, staining PDE1A in paraformaldehyde fixed HeLa by Immunofluorescence.
Lower image is merged with DNA probe.
Anti-PDE1A antibody (ab96336)参考文献
This product has been referenced in:
et al. Adenoviral short hairpin RNA therapy targeting phosphodiesterase 5a relieves cardiac remodeling and dysfunction following myocardial infarction. Am J Physiol Heart Circ Physiol 302:H2112-21 (2012).
Read more (PubMed: 22447941) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"