概述

  • 产品名称Anti-PDE12抗体
    参阅全部 PDE12 一抗
  • 描述
    兔多克隆抗体to PDE12
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide corresponding to a region within C terminal amino acids 369-398 of Human PDE12 (NP_808881.3).

  • 阳性对照
    • MDA-MB231 cell line lysate

性能

应用

Our Abpromise guarantee covers the use of ab107000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 67 kDa.

靶标

  • 功能Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Play a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the CCR4/nocturin family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2 PDE antibody
    • 2' 5' phosphodiesterase 12 antibody
    • 2' phosphodiesterase antibody
    • 2',5'-phosphodiesterase 12 antibody
    • 2'-PDE antibody
    • 2-PDE antibody
    • 2PDE antibody
    • DKFZp667B1218 antibody
    • Pde12 antibody
    • PDE12_HUMAN antibody
    • Phosphodiesterase 12 antibody
    see all

Anti-PDE12 antibody 图像

  • Anti-PDE12 antibody (ab107000) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

    Predicted band size : 67 kDa

Anti-PDE12 antibody (ab107000)参考文献

ab107000 has not yet been referenced specifically in any publications.

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