Anti-PDCD6抗体, prediluted (ab64104)

概述

  • 产品名称Anti-PDCD6抗体, prediluted
    参阅全部 PDCD6 一抗
  • 描述
    兔多克隆抗体to PDCD6, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to the C-terminal of human PDCD6.

  • 阳性对照
    • Human lung carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab64104 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready-to-use for 30 min at room temperature. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)-regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.
    • 序列相似性Contains 5 EF-hand domains.
    • 细胞定位Nucleus membrane. Endoplasmic reticulum membrane. Nucleus. Endosome. Interaction with RBM22 induces relocalization from the cytoplasm to the nucleus. Translocated from the cytoplasm to the nucleus after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AIP1 antibody
      • ALG 2 antibody
      • ALG-2-interacting protein 1 antibody
      • ALG2 antibody
      • ALIX antibody
      • Apoptosis linked gene 2 antibody
      • Apoptosis linked gene 2 protein antibody
      • Apoptosis-linked gene 2 protein antibody
      • FLJ42309 antibody
      • FLJ46208 antibody
      • Hp95 antibody
      • KIAA1375 antibody
      • MA 3 antibody
      • MA3 antibody
      • MGC111017 antibody
      • MGC119050 antibody
      • MGC9123 antibody
      • PDCD 6 antibody
      • Pdcd6 antibody
      • PDCD6_HUMAN antibody
      • PEF 1B antibody
      • PEF1B antibody
      • Probable calcium binding protein ALG 2 antibody
      • Probable calcium binding protein ALG2 antibody
      • Probable calcium-binding protein ALG-2 antibody
      • Programmed cell death 6 antibody
      • Programmed cell death 6-interacting protein antibody
      • Programmed cell death protein 6 antibody
      • PS 2 antibody
      • PS2 antibody
      see all

    Anti-PDCD6 antibody, prediluted 图像

    • Immunohistochemical analysis of PDCD6 expression in human lung carcinoma using ab64104 on formalin-fixed, paraffin-embedded tissue. Staining pattern: Cytoplasmic and cell membrane.

    Anti-PDCD6 antibody, prediluted (ab64104)参考文献

    ab64104 has not yet been referenced specifically in any publications.

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