Anti-PDCD6抗体- Carboxyterminal end (ab64151)


  • 产品名称Anti-PDCD6抗体- Carboxyterminal end
    参阅全部 PDCD6 一抗
  • 描述
    兔多克隆抗体to PDCD6 - Carboxyterminal end
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to the C terminal of human PDCD6.

  • 阳性对照
    • Human lung carcinoma.



Our Abpromise guarantee covers the use of ab64151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Incubate for 30 minutes at room temperature.


  • 功能Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)-regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.
  • 序列相似性Contains 5 EF-hand domains.
  • 细胞定位Nucleus membrane. Endoplasmic reticulum membrane. Nucleus. Endosome. Interaction with RBM22 induces relocalization from the cytoplasm to the nucleus. Translocated from the cytoplasm to the nucleus after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AIP1 antibody
    • ALG 2 antibody
    • ALG-2-interacting protein 1 antibody
    • ALG2 antibody
    • ALIX antibody
    • Apoptosis linked gene 2 antibody
    • Apoptosis linked gene 2 protein antibody
    • Apoptosis-linked gene 2 protein antibody
    • FLJ42309 antibody
    • FLJ46208 antibody
    • Hp95 antibody
    • KIAA1375 antibody
    • MA 3 antibody
    • MA3 antibody
    • MGC111017 antibody
    • MGC119050 antibody
    • MGC9123 antibody
    • PDCD 6 antibody
    • Pdcd6 antibody
    • PDCD6_HUMAN antibody
    • PEF 1B antibody
    • PEF1B antibody
    • Probable calcium binding protein ALG 2 antibody
    • Probable calcium binding protein ALG2 antibody
    • Probable calcium-binding protein ALG-2 antibody
    • Programmed cell death 6 antibody
    • Programmed cell death 6-interacting protein antibody
    • Programmed cell death protein 6 antibody
    • PS 2 antibody
    • PS2 antibody
    see all

Anti-PDCD6 antibody - Carboxyterminal end 图像

  • Immunohistochemical analysis of PDCD6 expression in human lung carcinoma using ab64151, at 1/50 dilution, on formalin-fixed, paraffin-embedded tissue. Staining pattern: Cytoplasmic and cell membrane.

Anti-PDCD6 antibody - Carboxyterminal end (ab64151)参考文献

ab64151 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab64151.
Please use the links above to contact us or submit feedback about this product.