参阅全部 PCSK9 一抗
ICC/IF, WBmore details
Mouse, Rat, Human预测可用于:
Chimpanzee, Macaque Monkey, Gorilla, Marmoset (common)
Synthetic peptide from Mouse PCSK9 amino acids 152-163
- 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
- 存储溶液Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, Tris buffered saline, 0.5mg/ml BSA, pH 7.4
Concentration information loading...
- 纯度Immunogen affinity purified
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use at an assay dependent dilution. Predicted molecular weight: 74 kDa.
- 功能May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis.
- 组织特异性Expressed in neuro-epithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells.
- 疾病相关Defects in PCSK9 are the cause of familial hypercholesterolemia 3 (FH3) [MIM:603776]. FH3 inheritance is autosomal dominant.
- 序列相似性Belongs to the peptidase S8 family.
Contains 1 peptidase S8 domain.
- 翻译后修饰The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted enzyme.
Information by UniProt
- Convertase subtilisin/kexin type 9 preproprotein antibody
- FH3 antibody
- HCHOLA3 antibody
Anti-PCSK9 antibody (ab95478)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"