Anti-PCPTP1抗体[T10-AF4H11] (ab88958)

概述

  • 产品名称Anti-PCPTP1抗体[T10-AF4H11]
    参阅全部 PCPTP1 一抗
  • 描述
    小鼠单克隆抗体[T10-AF4H11] to PCPTP1
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant human PCPTP1 purified from E.coli

  • 阳性对照
    • Bosc23 cell lysate transfected with Myc/His/PCPTP1 (328-651aa).

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.03% Sodium Azide
    Constituents: 50% Glycerol, 0.01% BSA, HEPES, 0.15M Sodium chloride
  • Concentration information loading...
  • 纯度Ammonium Sulphate Precipitation
  • 克隆单克隆
  • 克隆编号T10-AF4H11
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab88958 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IP
  • 应用说明IP: Use at a concentration of 1 µg/200 µl pre-cleared cell lysate (at 1mg/ml).
    WB: 1/1000. Predicted molecular weight: 74 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.
    • 组织特异性Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.
    • 序列相似性Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily.
      Contains 1 tyrosine-protein phosphatase domain.
    • 细胞定位Cell membrane and Cytoplasm > perinuclear region. Locates to the perinuclear areas within the cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Ch-1PTPase antibody
      • Ch1 PTPase antibody
      • DKFZp781C1038 antibody
      • EC PTP antibody
      • ECPTP antibody
      • FLJ34328 antibody
      • MGC131968 antibody
      • MGC148170 antibody
      • NC PTPCOM1 antibody
      • NC-PTPCOM1 antibody
      • Protein tyrosine phosphatase Cr1PTPase precursor antibody
      • Protein tyrosine phosphatase NC PTPCOM1 antibody
      • Protein tyrosine phosphatase PCPTP1 antibody
      • Protein tyrosine phosphatase receptor type R antibody
      • Protein-tyrosine phosphatase PCPTP1 antibody
      • PTP SL antibody
      • PTPBR7 antibody
      • PTPRQ antibody
      • PTPRR antibody
      • PTPRR_HUMAN antibody
      • PTPSL antibody
      • R-PTP-R antibody
      • Receptor type tyrosine protein phosphatase R antibody
      • Receptor-type tyrosine-protein phosphatase R antibody
      see all

    Anti-PCPTP1 antibody [T10-AF4H11] 图像

    • All lanes : Anti-PCPTP1 antibody [T10-AF4H11] (ab88958) at 1/1000 dilution

      Lane 1 : Bosc23 cell lysate
      Lane 2 : Bosc23 cell lysate transfected with Myc/His/Tau (1-441aa)
      Lane 3 : Bosc23 cell lysate transfected with Myc/His/PCPTP1 (328-651aa)
      Lane 4 : Bosc23 cell lysate transfected with GFP-Ub+1


      Predicted band size : 74 kDa
      Observed band size : 38 kDa (why is the actual band size different from the predicted?)

    Anti-PCPTP1 antibody [T10-AF4H11] (ab88958)参考文献

    ab88958 has not yet been referenced specifically in any publications.

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