概述

  • 产品名称Anti-PCPTP1抗体
    参阅全部 PCPTP1 一抗
  • 描述
    鸡多克隆抗体to PCPTP1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide: MNFVDPKEID IPRHGTKNRY KTILPNPLSR VCLRPKNVTD SLSTYINANY IRGY, corresponding to N terminal amino acids 157-210 of PCPTP1

性能

应用

Our Abpromise guarantee covers the use of ab37240 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/2000. Predicted molecular weight: 47 kDa.

靶标

  • 功能Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.
  • 组织特异性Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.
  • 序列相似性Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • 细胞定位Cell membrane and Cytoplasm > perinuclear region. Locates to the perinuclear areas within the cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Ch-1PTPase antibody
    • Ch1 PTPase antibody
    • DKFZp781C1038 antibody
    • EC PTP antibody
    • ECPTP antibody
    • FLJ34328 antibody
    • MGC131968 antibody
    • MGC148170 antibody
    • NC PTPCOM1 antibody
    • NC-PTPCOM1 antibody
    • Protein tyrosine phosphatase Cr1PTPase precursor antibody
    • Protein tyrosine phosphatase NC PTPCOM1 antibody
    • Protein tyrosine phosphatase PCPTP1 antibody
    • Protein tyrosine phosphatase receptor type R antibody
    • Protein-tyrosine phosphatase PCPTP1 antibody
    • PTP SL antibody
    • PTPBR7 antibody
    • PTPRQ antibody
    • PTPRR antibody
    • PTPRR_HUMAN antibody
    • PTPSL antibody
    • R-PTP-R antibody
    • Receptor type tyrosine protein phosphatase R antibody
    • Receptor-type tyrosine-protein phosphatase R antibody
    see all

Anti-PCPTP1 antibody 图像

  • Anti-PCPTP1 antibody (ab37240) at 1/2000 dilution + E coli-derived fusion protein

    Secondary
    Goat anti-IgY-HRP at 1/1000 dilution

    Predicted band size : 47 kDa

Anti-PCPTP1 antibody (ab37240)参考文献

ab37240 has not yet been referenced specifically in any publications.

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