概述

  • 产品名称Anti-PCDHGA2抗体
  • 描述
    小鼠单克隆抗体to PCDHGA2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 223-332 of Human PCDHGA2

性能

应用

Our Abpromise guarantee covers the use of ab57528 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性PCDHGA2 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
    • 细胞定位Cell membrane; Single-pass type I membrane protein
    • 数据库链接
    • 别名
      • PCDH gamma A2 antibody
      • Protocadherin gamma A2 antibody
      • Protocadherin gamma subfamily A 2 antibody

    Anti-PCDHGA2 antibody 图像



    • Predicted band size : 101 kDa
      PCDHGA2 antibody (ab57528) at 1ug/lane + Raw cell lysate at 25ug/lane.

    Anti-PCDHGA2 antibody (ab57528)参考文献

    ab57528 has not yet been referenced specifically in any publications.

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