概述

  • 产品名称
  • 描述
    兔多克隆抗体to PCDH12
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 612-661 (SSRPFLLTTI VARDADSGAN GEPLYSIRSG NEAHLFILNP HTGQLFVNVT) of human PCDH12 (NP_057664).

  • 阳性对照
    • MCF7 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab82885 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 129 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Promotes homotypic calcium dependent aggregation and adhesion and clusters at intercellular junctions. Unable to bind to catenins, weakly associates with the cytoskeleton.
  • 组织特异性
    Expressed in highly vascularized tissues including the heart and placenta, but most tissues contain a low level of expression. Prominent expression in the spleen.
  • 序列相似性
    Contains 6 cadherin domains.
  • 细胞定位
    Cell membrane. Cell junction.
  • Information by UniProt
  • 数据库链接
  • 别名
    • PCD12_HUMAN antibody
    • Pcdh12 antibody
    • Protocadherin 12 antibody
    • Protocadherin-12 antibody
    • Vascular cadherin 2 antibody
    • Vascular cadherin-2 antibody
    • Vascular endothelial cadherin 2 antibody
    • Vascular endothelial cadherin-2 antibody
    • VE cadherin 2 antibody
    • VE-cad-2 antibody
    • VE-cadherin-2 antibody
    • VECAD2 antibody
    see all

Anti-PCDH12 antibody 图像

  • Anti-PCDH12 antibody (ab82885) at 1 µg/ml + MCF7 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 129 kDa
    Observed band size : 143 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 45 kDa,65 kDa. We are unsure as to the identity of these extra bands.

实验方案

Anti-PCDH12 antibody (ab82885)参考文献

ab82885 has not yet been referenced specifically in any publications.

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