概述

  • 产品名称Anti-PCCB抗体
    参阅全部 PCCB 一抗
  • 描述
    兔多克隆抗体to PCCB
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Pig, Zebrafish
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 167-450 of Human PCCB (NP_000523).

  • 阳性对照
    • HepG2 cell lysate for WB and Lung Ad Cancer PC14 for IHC-P

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab96729 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/250.
WB 1/500 - 1/3000. Predicted molecular weight: 58 kDa.

靶标

  • 通路Metabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 1/3.
  • 疾病相关Defects in PCCB are the cause of propionic acidemia type II (PA-2) [MIM:606054]. PA-2 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.
  • 序列相似性Belongs to the AccD/PCCB family.
    Contains 1 carboxyltransferase domain.
  • 细胞定位Mitochondrion matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp451E113 antibody
    • PCCase subunit beta antibody
    • pccB antibody
    • PCCB_HUMAN antibody
    • pccBC Complementation group antibody
    • Propanoyl CoA:carbon dioxide ligase subunit beta antibody
    • Propanoyl-CoA:carbon dioxide ligase subunit beta antibody
    • Propionyl CoA carboxylase beta chain, mitochondrial antibody
    • propionyl Coenzyme A carboxylase, beta polypeptide antibody
    • Propionyl-CoA carboxylase , beta subunit antibody
    • Propionyl-CoA carboxylase beta chain, mitochondrial antibody
    • R74805 antibody
    see all

Anti-PCCB antibody 图像

  • Anti-PCCB antibody (ab96729) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 58 kDa
  • Immunohistochemical analysis of paraffin-embedded Lung Ad Cancer PC14, using ab96729 at 1:100 dilution.

Anti-PCCB antibody (ab96729)参考文献

ab96729 has not yet been referenced specifically in any publications.

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