概述

  • 产品名称Anti-PCCA抗体
    参阅全部 PCCA 一抗
  • 描述
    小鼠多克隆抗体to PCCA
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human PCCA (AAH00140.1)

  • 阳性对照
    • PCCA transfected 293T cell lysate and Human liver tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab89784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 77 kDa.

靶标

  • 通路Metabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 1/3.
  • 疾病相关Defects in PCCA are the cause of propionic acidemia type I (PA-1) [MIM:606054]. PA-1 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.
  • 序列相似性Contains 1 ATP-grasp domain.
    Contains 1 biotin carboxylation domain.
    Contains 1 biotinyl-binding domain.
  • 细胞定位Mitochondrion matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • mitochondrial antibody
    • Pcca antibody
    • pccA COMPLEMENTATION GROUP antibody
    • PCCA_HUMAN antibody
    • PCCase subunit alpha antibody
    • Propanoyl CoA:carbon dioxide ligase subunit alpha antibody
    • Propanoyl-CoA:carbon dioxide ligase subunit alpha antibody
    • Propionyl CoA carboxylase alpha chain antibody
    • Propionyl CoA carboxylase alpha chain mitochondrial antibody
    • Propionyl CoA carboxylase alpha polypeptide antibody
    • Propionyl coenzyme A carboxylase alpha polypeptide antibody
    • Propionyl-CoA carboxylase alpha chain antibody
    see all

Anti-PCCA antibody 图像

  • Anti-PCCA antibody (ab89784) at 1 µg/ml + human liver tissue lysate at 50 µg

    Predicted band size : 77 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-PCCA antibody (ab89784) at 1 µg/ml

    Lane 1 : PCCA transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 77 kDa
    Observed band size : 77 kDa

Anti-PCCA antibody (ab89784)参考文献

ab89784 has not yet been referenced specifically in any publications.

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