Anti-PCBP2/hnRNP E2抗体(ab95942)

概述

  • 产品名称
    Anti-PCBP2/hnRNP E2抗体
    参阅全部 PCBP2/hnRNP E2 一抗
  • 描述
    兔多克隆抗体to PCBP2/hnRNP E2
  • 经测试应用
    适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide containing a sequence corresponding to a region within amino acids 299-362 (IIGRQGAKIN EIRQMSGAQI KIANPVEGST DRQVTITGSA ASISLAQYLI NVRLSSETGG MGSS) of Human PCBP2/hnRNP E2 (NP_114366).

  • 阳性对照
    • HepG2 whole cell lysate; HeLa cells; 293T, A431, H1299, and Raji cells

性能

应用

Our Abpromise guarantee covers the use of ab95942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 39 kDa.
ICC/IF 1/100 - 1/200.

靶标

  • 功能
    Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation.
  • 组织特异性
    Detected in all tissues examined.
  • 序列相似性
    Contains 3 KH domains.
  • 翻译后修饰
    Phosphorylated. The non-phosphorylated form(s) exhibited the strongest poly(rC)-binding activity.
  • 细胞定位
    Nucleus. Cytoplasm. Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Alpha CP2 antibody
    • Alpha-CP2 antibody
    • alphaCP-2 antibody
    • Cbp antibody
    • CTBP antibody
    • Heterogeneous nuclear ribonucleoprotein E2 antibody
    • Heterogenous nuclear ribonucleoprotein E2 antibody
    • hnRNP E2 antibody
    • hnRNP-E2 antibody
    • HNRNPE2 antibody
    • Hnrnpx antibody
    • HNRPE2 antibody
    • Hnrpx antibody
    • MGC110998 antibody
    • PCBP2 antibody
    • PCBP2_HUMAN antibody
    • poly(rC) binding protein 2 antibody
    • Poly(rC)-binding protein 2 antibody
    • Putative heterogeneous nuclear ribonucleoprotein X antibody
    • rCbinding protein 2 antibody
    see all

图片

  • Anti-PCBP2/hnRNP E2 antibody (ab95942) at 1/500 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 39 kDa
  • ab95942, at 1/200 dilution, staining PCBP2/hnRNP E2 in paraformaldehyde-fixed HeLa cells by Immunofluorescence. Right image is merged with DNA probe.

文献

ab95942 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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