概述

  • 产品名称Anti-PBXIP1抗体
    参阅全部 PBXIP1 一抗
  • 描述
    兔多克隆抗体to PBXIP1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between amino acids 175 and 225 of human PBXIP1 (NP_079033.3).

  • 阳性对照
    • Breast carcinoma, ovarian carcinoma,anaplastic tyroid carcinoma,pancreatic islet cell tumor,stomach adenocarcinoma,testicular seminoma,stomach adenocarcinoma,prostrate carcinoma,linitis plastica stomach cancer,metastatic lymph node,teratoma

性能

应用

Our Abpromise guarantee covers the use of ab84752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Likely to work on frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性PBXIP1 is a regulator of pre-B-cell leukemia transcription factors (BPXs) function. It inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. PBXIP1 also tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
    • 细胞定位Cytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol. Mainly localized in the cytoplasm, associated with microtubules. Detected in small amounts in the nucleus.
    • 数据库链接
    • 别名
      • 4732463H20Rik antibody
      • Hematopoietic PBX interacting protein antibody
      • HPIP antibody
      • MGC38361 antibody
      • Pre B cell leukemia homeobox interacting protein 1 antibody
      • RP11-307C12.2 antibody
      see all

    Anti-PBXIP1 antibody 图像

    • Detection of mouse HPIP by immunohistochemistry on formalin fixed, paraffin embedded sections of mouse teratoma , using ab84752 at a 1/100 dilution.
      Detection: DAB staining.
    • Detection of human HPIP by immunohistochemistry on formalin fixed, paraffin embedded sections of human ovarian carcinoma, using ab84752 at a 1/100 dilution.
      Detection: DAB staining.
    • Detection of human HPIP by immunohistochemistry immunofluorescence of human ovarian carcinoma, using ab84752 at 1/100 dilution.
      Detection: red fluorescent Goat anti-Rabbit IgG diluted 1/100.

    Anti-PBXIP1 antibody (ab84752)参考文献

    ab84752 has not yet been referenced specifically in any publications.

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