概述

  • 产品名称
    Anti-Pbx3抗体[EPR2833(2)]
    参阅全部 Pbx3 一抗
  • 描述
    兔单克隆抗体[EPR2833(2)] to Pbx3
  • 经测试应用
    适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)

  • 阳性对照
    • Human fetal brain, A431 and HeLa lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab109173 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 47 kDa.
  • 应用说明
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能
      Transcriptional activator that binds the sequence 5'-ATCAATCAA-3'.
    • 组织特异性
      Ubiquitously expressed.
    • 序列相似性
      Belongs to the TALE/PBX homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • 细胞定位
      Nucleus.
    • Information by UniProt
    • 数据库链接
    • 形式
      There are 4 isoforms produced by alternative splicing.
    • 别名
      • Homeobox protein PBX3 antibody
      • MGC134053 antibody
      • OTTHUMP00000064213 antibody
      • Pbx 3 antibody
      • Pbx3 antibody
      • PBX3_HUMAN antibody
      • Pre B cell leukemia homeobox 3 antibody
      • Pre B cell leukemia transcription factor 3 antibody
      • Pre-B-cell leukemia transcription factor 3 antibody
      • RP11 336P12.1 antibody
      see all

    图片

    • All lanes : Anti-Pbx3 antibody [EPR2833(2)] (ab109173) at 1/1000 dilution

      Lane 1 : Human fetal brain lysate
      Lane 2 : A431 cell lysate
      Lane 3 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 47 kDa

    实验方案

    文献

    This product has been referenced in:
    • Han H  et al. PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells. Nat Commun 6:8271 (2015). Read more (PubMed: 26420065) »
    • Jiang X  et al. miR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia. Proc Natl Acad Sci U S A 109:19397-402 (2012). WB . Read more (PubMed: 23132946) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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