Anti-Paxillin (phospho Y31)抗体[M102] (ab24786)

概述

  • 产品名称Anti-Paxillin (phospho Y31)抗体[M102]
    参阅全部 Paxillin 一抗
  • 描述
    小鼠单克隆抗体[M102] to Paxillin (phospho Y31)
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human) conjugated to KLH corresponding to amino acid residues around Tyrosine 31 of human Paxillin.

性能

应用

Our Abpromise guarantee covers the use of ab24786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: 1/2000.
    WB: 1/1000. Detects a band of approximately 72 kDa corresponding to the molecular mass of phosphorylated paxillin on SDS PAGE immunoblots of pervanadate treated A431 cells, but not in A431 control cells.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
    • 序列相似性Belongs to the paxillin family.
      Contains 4 LIM zinc-binding domains.
    • 翻译后修饰Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens.
    • 细胞定位Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ16691 antibody
      • FLJ23042 antibody
      • Paired box protein Pax 1 antibody
      • PAX 1 antibody
      • PAX1 antibody
      • PAXI_HUMAN antibody
      • Paxillin alpha antibody
      • Paxillin antibody
      • PXN antibody
      • PXN protein antibody
      see all

    Anti-Paxillin (phospho Y31) antibody [M102] 图像

    • All lanes : Anti-Paxillin (phospho Y31) antibody [M102] (ab24786)

      Lane 1 : A431 cells (30 mg/lane) serum starved overnight
      Lane 2 : A431 cells (30 mg/lane) treated with pervanadate (1 mMl) for 30 min.

    Anti-Paxillin (phospho Y31) antibody [M102] (ab24786)参考文献

    ab24786 has not yet been referenced specifically in any publications.

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