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RabMAb

Anti-Paxillin (phospho Y118)抗体[EPR1903] (ab109547)

概述

  • 产品名称
    Anti-Paxillin (phospho Y118)抗体[EPR1903]
    参阅全部 Paxillin 一抗
  • 描述
    兔单克隆抗体[EPR1903] to Paxillin (phospho Y118)
  • 特异性
    The antibody only detects Paxillin phosphorylated on Tyrosine 118.
  • 经测试应用
    适用于: WBmore details
    不适用于: Flow Cyt,ICC/IF,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A synthetic phospho-peptide corresponding to residues surrounding Tyrosine 118 of Human Paxillin

  • 阳性对照
    • HeLa cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

应用

Our Abpromise guarantee covers the use of ab109547 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 65 kDa.
  • 应用说明
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • 靶标

    • 功能
      Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
    • 序列相似性
      Belongs to the paxillin family.
      Contains 4 LIM zinc-binding domains.
    • 翻译后修饰
      Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens.
    • 细胞定位
      Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ16691 antibody
      • FLJ23042 antibody
      • Paired box protein Pax 1 antibody
      • PAX 1 antibody
      • PAX1 antibody
      • PAXI_HUMAN antibody
      • Paxillin alpha antibody
      • Paxillin antibody
      • PXN antibody
      • PXN protein antibody
      see all

    Anti-Paxillin (phospho Y118) antibody [EPR1903] 图像

    • All lanes : Anti-Paxillin (phospho Y118) antibody [EPR1903] (ab109547) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HeLa cell lysate treated with pervanadate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 65 kDa

    实验方案

    Anti-Paxillin (phospho Y118) antibody [EPR1903] (ab109547)参考文献

    This product has been referenced in:
    • Kishi T  et al. Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity. Oncotarget 7:72113-72130 (2016). Read more (PubMed: 27708220) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab109547.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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