Anti-Paxillin (phospho Y118)抗体(ab38466)

概述

  • 产品名称Anti-Paxillin (phospho Y118)抗体
    参阅全部 Paxillin 一抗
  • 描述
    兔多克隆抗体to Paxillin (phospho Y118)
  • 特异性This antibody is specific for Paxillin only when phosphorylated at tyrosine 118.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic phosphopeptide derived from Human Paxillin around the phosphorylation site of tyrosine 118 (HVYpSF).

  • 阳性对照
    • Hela cell extract.

性能

应用

Our Abpromise guarantee covers the use of ab38466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: 1/10,000.
    WB: 1/500 - 1/1000. Detects a band of approximately 64 kDa (predicted molecular weight: 64 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
    • 序列相似性Belongs to the paxillin family.
      Contains 4 LIM zinc-binding domains.
    • 翻译后修饰Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens.
    • 细胞定位Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ16691 antibody
      • FLJ23042 antibody
      • Paired box protein Pax 1 antibody
      • PAX 1 antibody
      • PAX1 antibody
      • PAXI_HUMAN antibody
      • Paxillin alpha antibody
      • Paxillin antibody
      • PXN antibody
      • PXN protein antibody
      see all

    Anti-Paxillin (phospho Y118) antibody 图像

    • All lanes : Anti-Paxillin (phospho Y118) antibody (ab38466) at 1/500 dilution

      Lane 1 : Hela cell extract + EGF (Cells were treated with 200ng/ml EGF for 20 minutes)
      Lane 2 : Hela cell extract

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 64 kDa

    Anti-Paxillin (phospho Y118) antibody (ab38466)参考文献

    ab38466 has not yet been referenced specifically in any publications.

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