Anti-Paxillin (phospho S83)抗体(ab31833)

概述

  • 产品名称
    Anti-Paxillin (phospho S83)抗体
    参阅全部 Paxillin 一抗
  • 描述
    兔多克隆抗体to Paxillin (phospho S83)
  • 特异性
    ab31833 detects a 68kDa protein corresponding to the molecular mass of phosphorylated paxillin.
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Synthetic peptide (Mouse) conjugated to KLH corresponding to amino acid residues around serine 83 of paxillin.

  • 阳性对照
    • Calyculin A treated mouse macrophages.

性能

应用

Our Abpromise guarantee covers the use of ab31833 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明
    ELISA: 1/2000.
    WB: 1/1000 (in 5% non-fat milk, PBS, 0.04% Tween20 for 1hour at room temperature). Predicted molecular weight: 68 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
    • 序列相似性
      Belongs to the paxillin family.
      Contains 4 LIM zinc-binding domains.
    • 翻译后修饰
      Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens.
    • 细胞定位
      Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ16691 antibody
      • FLJ23042 antibody
      • Paired box protein Pax 1 antibody
      • PAX 1 antibody
      • PAX1 antibody
      • PAXI_HUMAN antibody
      • Paxillin alpha antibody
      • Paxillin antibody
      • PXN antibody
      • PXN protein antibody
      see all

    图片



    • Predicted band size : 68 kDa

    实验方案

    文献

    ab31833 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    Thank you for your enquiry. This antibody has yet to be tested in human or monkey tissue. The conserved site in human paxillin (Ser-83) has high homology with the mouse paxillin (Ser-83). There is only 2 amino acid differences, however there ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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