概述

  • 产品名称Anti-PAX7抗体
    参阅全部 PAX7 一抗
  • 描述
    兔多克隆抗体to PAX7
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Three synthetic peptides (Human) conjugated to KLH

  • 阳性对照
    • An induced culture of E. coli

性能

应用

Our Abpromise guarantee covers the use of ab86026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/1000. Detects a band of approximately 71 kDa (predicted molecular weight: 57 kDa). Tag is 14kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Probable transcription factor. May have a role in myogenesis.
    • 疾病相关Defects in PAX7 are a cause of rhabdomyosarcoma type 2 (RMS2) [MIM:268220]. It is a form of rhabdomyosarcoma, a highly malignant tumor of striated muscle derived from primitive mesenchimal cells and exhibiting differentiation along rhabdomyoblastic lines. Rhabdomyosarcoma is one of the most frequently occurring soft tissue sarcomas and the most common in children. It occurs in four forms: alveolar, pleomorphic, embryonal and botryoidal rhabdomyosarcomas. Note=A chromosomal aberration involving PAX7 is found in rhabdomyosarcoma. Translocation t(1;13)(p36;q14) with FOXO1. The resulting protein is a transcriptional activator.
    • 序列相似性Belongs to the paired homeobox family.
      Contains 1 homeobox DNA-binding domain.
      Contains 1 paired domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ37460 antibody
      • HUP1 antibody
      • OTTHUMP00000002534 antibody
      • Paired box 7 antibody
      • Paired box gene 7 antibody
      • Paired box homeotic gene 7 antibody
      • Paired box protein Pax-7 antibody
      • Paired domain gene 7 antibody
      • Paired domain gene HuP1 antibody
      • Pax7 antibody
      • PAX7 transcriptional factor antibody
      • PAX7/FKHR fusion gene, included antibody
      • PAX7_HUMAN antibody
      • PAX7B antibody
      • RGD1564360 antibody
      • RMS2 antibody
      see all

    Anti-PAX7 antibody 图像

    • All lanes : Anti-PAX7 antibody (ab86026) at 1/1000 dilution

      Lane 1 : An un-induced culture of E. coli
      Lane 2 : An induced culture of E. coli

      Secondary
      Anti-Rabbit IgG HRP at 1/1000 dilution

      Predicted band size : 57 kDa
      Observed band size : 31,34,71 kDa (why is the actual band size different from the predicted?)


      Exposure time : 60 minutes

    Anti-PAX7 antibody (ab86026)参考文献

    ab86026 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"