概述
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产品名称Anti-PAX7抗体
参阅全部 PAX7 一抗 -
描述兔多克隆抗体to PAX7
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宿主Rabbit
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经测试应用适用于: WBmore details
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种属反应性与反应: Mouse, Human
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免疫原
Three synthetic peptides (Human) conjugated to KLH
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阳性对照
- An induced culture of E. coli
性能
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形式Liquid
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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存储溶液Preservative: 0.01% Thimerosal (merthiolate)
Constituents: Whole serum -
纯度Whole antiserum
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab86026 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
应用说明
WB: 1/1000. Detects a band of approximately 71 kDa (predicted molecular weight: 57 kDa). Tag is 14kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能Probable transcription factor. May have a role in myogenesis.
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疾病相关Defects in PAX7 are a cause of rhabdomyosarcoma type 2 (RMS2) [MIM:268220]. It is a form of rhabdomyosarcoma, a highly malignant tumor of striated muscle derived from primitive mesenchimal cells and exhibiting differentiation along rhabdomyoblastic lines. Rhabdomyosarcoma is one of the most frequently occurring soft tissue sarcomas and the most common in children. It occurs in four forms: alveolar, pleomorphic, embryonal and botryoidal rhabdomyosarcomas. Note=A chromosomal aberration involving PAX7 is found in rhabdomyosarcoma. Translocation t(1;13)(p36;q14) with FOXO1. The resulting protein is a transcriptional activator.
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序列相似性Belongs to the paired homeobox family.
Contains 1 homeobox DNA-binding domain.
Contains 1 paired domain. -
细胞定位Nucleus.
- Information by UniProt
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数据库链接
- Entrez Gene: 5081 Human
- Entrez Gene: 18509 Mouse
- Omim: 167410 Human
- SwissProt: P23759 Human
- SwissProt: P47239 Mouse
- Unigene: 113253 Human
- Unigene: 218760 Mouse
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别名
- FLJ37460 antibody
- HUP1 antibody
- OTTHUMP00000002534 antibody
see all
图片
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Western blot - Anti-PAX7 antibody (ab86026)All lanes : Anti-PAX7 antibody (ab86026) at 1/1000 dilution
Lane 1 : An un-induced culture of E. coli
Lane 2 : An induced culture of E. coli
Secondary
All lanes : Anti-Rabbit IgG HRP at 1/1000 dilution
Predicted band size: 57 kDa
Observed band size: 31,34,71 kDa (why is the actual band size different from the predicted?)
Exposure time: 60 minutes
Gel concentration 10%
文献
ab86026 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"