Anti-PAX5抗体(ab2935)

概述

  • 产品名称Anti-PAX5抗体
    参阅全部 PAX5 一抗
  • 描述
    山羊多克隆抗体to PAX5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide: DLEKNYPTPRTSR, corresponding to N terminal amino acids 2-14 of Human PAX5.

  • 阳性对照
    • U937 lysate
  • 常规说明Principal Names – PAX5; BSAP; paired box gene 5 (B-cell lineage specific activator protein); B-cell lineage specific activator protein; paired box homeotic gene 5 (B-cell lineage specific activator protein) Official Gene Symbol - PAX5 GenBank Accession Number – NP_057953 LocusLink ID - 5079 (human) Gene Ontology terms - transcription activating factor; humoral immune response; histogenesis and organogenesis; development; oncogenesis; transcription from Pol II promoter

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab2935 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 2 - 4 µg/ml. Detects a band of approximately 51 kDa in U937 cells (predicted molecular weight: 42 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
    • 疾病相关A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6.
      Leukemia, acute lymphoblastic, 3
    • 序列相似性Contains 1 paired domain.
    • 发展阶段Expressed at early B-cell differentiation, in the developing CNS and in adult testis.
    • 翻译后修饰O-glycosylated.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • B cell lineage specific activator antibody
      • B cell lineage specific activator protein antibody
      • B cell specific activator protein antibody
      • B cell specific transcription factor antibody
      • B-cell-specific transcription factor antibody
      • BSAP antibody
      • EBB-1 antibody
      • KLP antibody
      • Paired box 5 antibody
      • Paired box gene 5 (B cell lineage specific activator protein) antibody
      • Paired box gene 5 (B cell lineage specific activator) antibody
      • Paired box gene 5 antibody
      • Paired box homeotic gene 5 antibody
      • Paired box protein Pax 5 antibody
      • Paired box protein Pax-5 antibody
      • Paired domain gene 5 antibody
      • PAX 5 antibody
      • PAX5 antibody
      • PAX5_HUMAN antibody
      • Transcription factor PAX 5 antibody
      see all

    Anti-PAX5 antibody 图像



    • Predicted band size : 42 kDa


      ab2935 staining (3µg/ml) of U937 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

    Anti-PAX5 antibody (ab2935)参考文献

    ab2935 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your patience. I am sorry to hear that you are experiencing difficulties with this product ab2935 in immunohistochemistry. Often it is possible to make suggestions that help resolve problems. We will happily offer technical support bu...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"