概述

  • 产品名称Anti-PARP9抗体
    参阅全部 PARP9 一抗
  • 描述
    兔多克隆抗体to PARP9
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 144-193 (LHGGGLALAL VKAGGFEIQE ESKQFVARYG KVSAGEIAVT GAGRLPCKQI) of human PARP9 (NP_113646).

  • 阳性对照
    • Fetal brain lysate.

性能

应用

Our Abpromise guarantee covers the use of ab83010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 96 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Involved in inducing the expression of IFN-gamma-responsive genes.
  • 组织特异性Expressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form. Most abundantly expressed in lymphomas with a brisk host inflammatory response. In diffuse large B-cell lymphomas tumors, expressed specifically by malignant B-cells.
  • 疾病相关Note=Overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression in B-cell lymphoma transfectants may promote malignant B-cell migration. May therefore be involved in promoting B-cell migration and dissemination of high-risk DLB-CL tumors.
  • 序列相似性Contains 2 Macro domains.
    Contains 1 PARP catalytic domain.
  • 细胞定位Cytoplasm > cytosol. Nucleus. Shuttles between the nucleus and the cytosol. Export to the cytosol depends on the interaction with DTX3L.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ADP-ribosyltransferase diphtheria toxin-like 9 antibody
    • ARTD9 antibody
    • AW214463 antibody
    • B aggressive lymphoma protein antibody
    • Bagl antibody
    • BAL antibody
    • BAL1 antibody
    • BC003281 antibody
    • DKFZp666B0810 antibody
    • DKFZp686M15238 antibody
    • EC 2.4.2.30 antibody
    • FLJ26637 antibody
    • FLJ35310 antibody
    • FLJ41418 antibody
    • FLJ43593 antibody
    • MGC:7868 antibody
    • MGC156739 antibody
    • MGC7868 antibody
    • OTTMUSP00000028034 antibody
    • PARP 9 antibody
    • PARP-9 antibody
    • Parp9 antibody
    • PARP9_HUMAN antibody
    • Poly (ADP ribose) polymerase family member 9 antibody
    • Poly [ADP-ribose] polymerase 9 antibody
    • RGD1307534 antibody
    see all

Anti-PARP9 antibody 图像

  • Anti-PARP9 antibody (ab83010) at 1 µg/ml + Fetal brain lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 96 kDa
    Observed band size : >90 kDa (why is the actual band size different from the predicted?)

Anti-PARP9 antibody (ab83010)参考文献

ab83010 has not yet been referenced specifically in any publications.

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