Anti-Parathyroid Hormone抗体[BGN/1F8] (ab63993)

概述

  • 产品名称Anti-Parathyroid Hormone抗体[BGN/1F8]
    参阅全部 Parathyroid Hormone 一抗
  • 描述
    小鼠单克隆抗体[BGN/1F8] to Parathyroid Hormone
  • 经测试应用适用于: ELISA, IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Cow, Dog, Pig, Deer, Orangutan
  • 免疫原

    Synthetic peptide: corresponding to amino acids 1-34 of (human) mature PTH conjugated to a proprietary carrier molecule. Ref: NCBI AAA72730.1

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 克隆编号BGN/1F8
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab63993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use a concentration of 1 - 10 µg/ml.
IHC-P Use a concentration of 10 µg/ml.
IHC-Fr Use a concentration of 10 µg/ml.

靶标

  • 功能PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
  • 疾病相关Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
  • 序列相似性Belongs to the parathyroid hormone family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • hPTH antibody
    • Parathormone antibody
    • Parathyrin antibody
    • Parathyroid hormone 1 antibody
    • Parathyroid hormone antibody
    • PTH antibody
    • PTH1 antibody
    • PTH1 receptor antibody
    • PTH1R antibody
    • PTHR antibody
    • PTHR1 antibody
    • PTHY_HUMAN antibody
    see all

Anti-Parathyroid Hormone antibody [BGN/1F8] (ab63993)参考文献

ab63993 has not yet been referenced specifically in any publications.

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Thank you for your inquiry.


The antibody ab63993 has not been tested in WB, however, based on the SwissProt information the protein is about 13 kDa. To detect such a small protein, you're going to have to use a high percentage gel, like...

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Thank you for contacting Abcam. All the antibodies in our catalogue are research use only (RUO). Please let me know if there is anything else I can do to help.

Abcam has not validated the combination of species/application used in this Abreview.
Application ELISA
Sample Rat Recombinant protein (PTH calbiochem #12585)
Specification PTH calbiochem #12585
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 2% · Temperature: 28°C
Type Indirect
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提交于 Sep 08 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"