Anti-Parathyroid Hormone抗体[B1/70] (ab14496)

概述

  • 产品名称Anti-Parathyroid Hormone抗体[B1/70]
    参阅全部 Parathyroid Hormone 一抗
  • 描述
    小鼠单克隆抗体[B1/70] to Parathyroid Hormone
  • 特异性Ab14496 reacts with parathyroid hormone peptides:aa 15-25; 1-34; 1-38; 1-84; 7-84. There are no cross reactivities with parathyroid hormone peptides: aa 1-3; 1-10; 4-16; 28-48; 39-84; 44-68; 53-84; PTHrP aa 1- 86.
  • 经测试应用适用于: ELISA, IHC-P, IHC-Fr, RIAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Horse, Cow, Cat, Dog, Pig, Macaque Monkey
  • 免疫原

    Poly Lysin conjugated synthetic peptide:

    SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFVALG

    , corresponding to amino acids 1-38 of Human Parathyroid Hormone.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.05% Sodium Azide
    Constituents: 50mM Tris. pH 7.4
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 克隆编号B1/70
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab14496 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
IHC-P
IHC-Fr
RIA
  • 应用说明ELISA: Use at a concentration of 1 µg/ml.
    IHC-P: Use at a concentration of 2 µg/ml.
    IHC-Fr: Use at a concentration of 2 µg/ml.
    RIA: Use at a concentration of 25 ng/ml.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
    • 疾病相关Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
    • 序列相似性Belongs to the parathyroid hormone family.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • hPTH antibody
      • Parathormone antibody
      • Parathyrin antibody
      • Parathyroid hormone 1 antibody
      • Parathyroid hormone antibody
      • PTH antibody
      • PTH1 antibody
      • PTH1 receptor antibody
      • PTH1R antibody
      • PTHR antibody
      • PTHR1 antibody
      • PTHY_HUMAN antibody
      see all

    Anti-Parathyroid Hormone antibody [B1/70] (ab14496)参考文献

    ab14496 has not yet been referenced specifically in any publications.

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