概述

  • 产品名称Anti-Parathyroid Hormone抗体
    参阅全部 Parathyroid Hormone 一抗
  • 描述
    山羊多克隆抗体to Parathyroid Hormone
  • 经测试应用适用于: Functional Studies, RIAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human Parathyroid Hormone aa 1-38. Human PTH (aa 12-17; 1-34; 1-38; 1-84).
    Sequence:

    SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 纯度Whole antiserum
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab14164 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Functional Studies Use at an assay dependent concentration. PubMed: 21389278Used to block PTH activity
RIA 1/30000.

靶标

  • 功能PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
  • 疾病相关Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
  • 序列相似性Belongs to the parathyroid hormone family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • hPTH antibody
    • Parathormone antibody
    • Parathyrin antibody
    • Parathyroid hormone 1 antibody
    • Parathyroid hormone antibody
    • PTH antibody
    • PTH1 antibody
    • PTH1 receptor antibody
    • PTH1R antibody
    • PTHR antibody
    • PTHR1 antibody
    • PTHY_HUMAN antibody
    see all

Anti-Parathyroid Hormone antibody (ab14164)参考文献

This product has been referenced in:
  • Laohapitakworn S  et al. Parathyroid hormone (PTH) rapidly enhances CFTR-mediated HCOFormula secretion in intestinal epithelium-like Caco-2 monolayer: a novel ion regulatory action of PTH. Am J Physiol Cell Physiol 301:C137-49 (2011). Functional Studies ; Human . Read more (PubMed: 21389278) »

See 1 Publication for this product

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