Anti-Parathyroid Hormone抗体[A1/70] (ab14493)

概述

  • 产品名称Anti-Parathyroid Hormone抗体[A1/70]
    参阅全部 Parathyroid Hormone 一抗
  • 描述
    小鼠单克隆抗体[A1/70] to Parathyroid Hormone
  • 特异性ab14493 recognises parathyroid hormone peptides (aa 15-25; 1-34; 1-38; 1-84; 7-84). There are no cross reactivities obtained with synthetic parathyroid hormone peptides (aa 1-3; 1-10; 4-16; 28-48; 39-84; 44-68; 53-84) and PTHrP (aa 1-86).
  • 经测试应用适用于: ELISA, RIA, IHC-Fr, IHC-P, Sandwich ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Cow, Cat, Dog, Pig, Cynomolgus Monkey
  • 免疫原

    Poly lysin conjugated synthetic peptide:

    SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFVALG

    , corresponding to amino acids 1-38 of Human Parathyroid Hormone.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 0.15M Sodium Chloride, 0.01M Sodium Phosphate. pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明Cell supernatant, Prot. A purified.
  • 克隆单克隆
  • 克隆编号A1/70
  • 同种型IgA
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab14493 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use a concentration of 1 µg/ml.
RIA Use at an assay dependent concentration. Use at a concentration of 2 ng/ml
IHC-Fr Use a concentration of 2 µg/ml.
IHC-P Use a concentration of 2 µg/ml.
Sandwich ELISA Use a concentration of 0.2 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to Parathyroid Hormone (ab53040). For sandwich ELISA, use this antibody as Capture at 0.2µg/ml with ab53040 as Detection.

靶标

  • 功能PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
  • 疾病相关Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
  • 序列相似性Belongs to the parathyroid hormone family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • hPTH antibody
    • Parathormone antibody
    • Parathyrin antibody
    • Parathyroid hormone 1 antibody
    • Parathyroid hormone antibody
    • PTH antibody
    • PTH1 antibody
    • PTH1 receptor antibody
    • PTH1R antibody
    • PTHR antibody
    • PTHR1 antibody
    • PTHY_HUMAN antibody
    see all

Anti-Parathyroid Hormone antibody [A1/70] 图像

实验方案

Anti-Parathyroid Hormone antibody [A1/70] (ab14493)参考文献

ab14493 has not yet been referenced specifically in any publications.

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