Anti-PAR2抗体(ab124227)
Key features and details
- Rabbit polyclonal to PAR2
- Suitable for: IHC-P
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-PAR2抗体
参阅全部 PAR2 一抗 -
描述
兔多克隆抗体to PAR2 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Rat -
免疫原
Synthetic peptide within Human PAR2 aa 300-370 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary. The immunogen is directed against a cytoplasmic region of PAR2.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Contains antibody stabilization buffer. -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab123227 is purified on an antigen-based affinity column. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab124227于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P | (1) |
1/100.
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说明 |
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IHC-P
1/100. |
靶标
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功能
Receptor for trypsin and trypsin-like enzymes coupled to G proteins that stimulate phosphoinositide hydrolysis. May have a role in the regulation of vascular tone. -
组织特异性
Widely expressed in tissues with especially high levels in pancreas, liver, kidney, small intestine, and colon. Moderate expression is detected in many organs, but none in brain or skeletal muscle. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
翻译后修饰
A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 116677 Rat
- SwissProt: Q63645 Rat
- Unigene: 10543 Rat
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别名
- Coagulation factor II receptor like 1 antibody
- Coagulation factor II receptor-like 1 antibody
- Coagulation factor II thrombin receptor like 1 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat spleen tissue labelling PAR2 with ab124227 at 1/100 dilution. Counterstained with hematoxylin. 40X magnification.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat spleen tissue labelling PAR2 with ab124227 at 1/100 dilution. Counterstained with hematoxylin. 5X magnification.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (3)
ab124227 被引用在 3 文献中.
- Huuskonen MT et al. Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C. J Exp Med 219:N/A (2022). PubMed: 34846535
- Sokolina K et al. Systematic protein-protein interaction mapping for clinically relevant human GPCRs. Mol Syst Biol 13:918 (2017). IP . PubMed: 28298427
- Li M et al. Activation of protease-activated receptor-2 is associated with increased expression of inflammatory factors in the adipose tissues of obese mice. Mol Med Rep 12:6227-34 (2015). PubMed: 26252901