概述

  • 产品名称
    Anti-PAPP A2抗体
    参阅全部 PAPP A2 一抗
  • 描述
    兔多克隆抗体to PAPP A2
  • 经测试应用
    适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region from the N-terminus of Human PAPP A2.

  • 阳性对照
    • Human Heart and Placenta tissues.

性能

应用

Our Abpromise guarantee covers the use of ab117743 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 199 kDa.Can be blocked with PAPP A2 peptide (ab215817).
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能
    Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3.
  • 组织特异性
    Expressed abundantly in placenta, and non-pregnant mammary gland with low expression in the kidney, fetal brain and pancreas.
  • 序列相似性
    Belongs to the peptidase M43B family.
    Contains 5 Sushi (CCP/SCR) domains.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • PAPPA 2 antibody
    • PAPP E antibody
    • PAPP-A2 antibody
    • PAPP-E antibody
    • PAPP2_HUMAN antibody
    • PAPPA2 antibody
    • Pappalysin 2 antibody
    • Pappalysin-2 antibody
    • PLAC3 antibody
    • Pregnancy associated plasma protein A2 antibody
    • Pregnancy associated plasma protein E1 antibody
    • Pregnancy-associated plasma protein A2 antibody
    • Pregnancy-associated plasma protein E1 antibody
    see all

图片

  • ab117743, at 5 µg/ml, staining PAPP A2 in Formalin-fixed, Paraffin-embedded Human heart tissue by Immunohistochemistry.
  • ab117743, at 5 µg/ml, staining PAPP A2 in Formalin-fixed, Paraffin-embedded Human Placenta tissue by Immunohistochemistry.

文献

ab117743 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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