Anti-PAPP A抗体[5H9] (HRP) (ab10191)


  • 产品名称Anti-PAPP A抗体[5H9] (HRP)
    参阅全部 PAPP A 一抗
  • 描述
    小鼠单克隆抗体[5H9] to PAPP A (HRP)
  • 偶联物HRP
  • 经测试应用适用于: WB, Sandwich ELISA, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Purified human PAPPA antigen.

  • 常规说明Concentration varies from lot to lot and can be provided on request.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.05% Proclin
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明Purified by chromatography on protein A Sepharose. Purity is tested by electrophoresis.
  • 克隆单克隆
  • 克隆编号5H9
  • 骨髓瘤Sp2/0
  • 同种型IgG2b
  • 研究领域


Our Abpromise guarantee covers the use of ab10191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution.
Sandwich ELISA Use at an assay dependent dilution. Can be used as detection antibody in conjunction with recommended pair for detection of htPAPP-A antigen in pregnancy serum.
ELISA Use at an assay dependent dilution.


  • 功能Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
  • 组织特异性High levels in placenta and pregnancy serum. In placenta, expressed in X cells in septa and anchoring villi, and in syncytiotrophoblasts in the chorionic villi. Lower levels are found in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow, colon, fibroblasts and osteoblasts.
  • 序列相似性Belongs to the peptidase M43B family.
    Contains 5 Sushi (CCP/SCR) domains.
  • 发展阶段Present in serum and placenta during pregnancy; levels increase throughout pregnancy.
  • 翻译后修饰There appear to be no free sulfhydryl groups.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ASBABP2 antibody
    • Aspecific BCL2 ARE binding protein 2 antibody
    • Differentially placenta 1 expressed protein antibody
    • DIPLA1 antibody
    • EC antibody
    • IGF dependent IGFBP 4 protease antibody
    • IGF-dependent IGFBP-4 protease antibody
    • IGFBP 4ase antibody
    • IGFBP-4ase antibody
    • IGFBP4ase antibody
    • Insulin like growth factor dependent IGF binding protein 4 protease antibody
    • Insulin-like growth factor-dependent IGF-binding protein 4 protease antibody
    • PAPA antibody
    • PAPP A antibody
    • PAPP-A antibody
    • PAPP1_HUMAN antibody
    • PAPPA antibody
    • PAPPA1 antibody
    • Pappalysin 1 precursor antibody
    • Pappalysin-1 antibody
    • Pregnancy Associated Plasma Protein A antibody
    • Pregnancy associated plasma protein A pappalysin 1 antibody
    • Pregnancy-associated plasma protein A antibody
    see all

Anti-PAPP A antibody [5H9] (HRP) (ab10191)参考文献

ab10191 has not yet been referenced specifically in any publications.

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