Anti-pan Sodium Channel抗体(ab53724)

概述

  • 产品名称Anti-pan Sodium Channel抗体
  • 描述
    兔多克隆抗体to pan Sodium Channel
  • 特异性Detects endogenous levels of total sodium channel protein.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to Human pan Sodium Channel.

  • 阳性对照
    • Extracts from HuvEc cells.

性能

应用

Our Abpromise guarantee covers the use of ab53724 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/20000.
WB 1/500 - 1/1000. Detects a band of approximately 227 kDa (predicted molecular weight: 227 kDa).

靶标

  • 相关性The pan sodium ion channel, SCN5A, is a cardiac sodium channel distinct from those in nerve and muscle. It is a tetrodotoxin-resistant Na(+) channel isoform. SCN5A mediates the voltage-dependent sodium ion permeability of excitable membranes by opening or closing in response to the voltage difference across the membrane. Na(+) ions pass in accordance with their electrochemical gradient. This channel is responsible for the initial upstroke of the action potential in the electrocardiogram. Defects in SCN5A are involved in many diseases including: progressive familial heart block type I (PFHBI), also known as Lenegre-Lev disease or progressive cardiac conduction defect (PCCD); long QT syndrome type 3 (LQT3); Brugada syndrome; sick sinus syndrome 1 (SSS1); idiopathic ventricular fibrillation (IVF), also called paroxysmal familial ventricular fibrillation; sudden infant death syndrome (SIDS); familial atrial standstill and dilated cardiomyopathy 1E (CMD1E).
  • 细胞定位Cell Membrane; Multi-pass membrane protein.
  • 数据库链接
  • 别名
    • HBSC II antibody
    • HH1 antibody
    • hNaN antibody
    • hNE-Na antibody
    • hPN3 antibody
    • KIAA1356 antibody
    • MED antibody
    • NAC1 antibody
    • NAC2 antibody
    • NAC3 antibody
    • NENA antibody
    • Neuroendocrine sodium channel antibody
    • Peripheral nerve sodium channel 3 antibody
    • Peripheral nerve sodium channel 5 antibody
    • Peripheral sodium channel 1 antibody
    • PN1 antibody
    • PN3 antibody
    • PN5 antibody
    • SCN1 antibody
    • SCN10A antibody
    • SCN11A antibody
    • SCN12A antibody
    • SCN1A antibody
    • SCN2A antibody
    • SCN2A1 antibody
    • SCN2A2 antibody
    • SCN3A antibody
    • SCN4A antibody
    • SCN5A antibody
    • SCN8A antibody
    • SCN9A antibody
    • Sensory neuron sodium channel 2 antibody
    • SkM1 antibody
    • SNS2 antibody
    • Sodium channel protein brain I subunit alpha antibody
    • Sodium channel protein brain II subunit alpha antibody
    • Sodium channel protein brain III subunit alpha antibody
    • Sodium channel protein cardiac muscle subunit alpha antibody
    • Sodium channel protein skeletal muscle subunit alpha antibody
    • Sodium channel protein type 1 subunit alpha antibody
    • Sodium channel protein type 10 subunit alpha antibody
    • Sodium channel protein type 11 subunit alpha antibody
    • Sodium channel protein type 2 subunit alpha antibody
    • Sodium channel protein type 3 subunit alpha antibody
    • Sodium channel protein type 4 subunit alpha antibody
    • Sodium channel protein type 5 subunit alpha antibody
    • Sodium channel protein type 8 subunit alpha antibody
    • Sodium channel protein type 9 subunit alpha antibody
    • Sodium channel protein type II subunit alpha antibody
    • Sodium channel protein type III subunit alpha antibody
    • Sodium channel protein type IV subunit alpha antibody
    • Sodium channel protein type IX subunit alpha antibody
    • Sodium channel protein type V subunit alpha antibody
    • Sodium channel protein type VIII subunit alpha antibody
    • Sodium channel protein type X subunit alpha antibody
    • Sodium channel protein type XI subunit alpha antibody
    • Voltage-gated sodium channel subtype III antibody
    • Voltage-gated sodium channel subunit alpha Nav1.1 antibody
    • Voltage-gated sodium channel subunit alpha Nav1.2 antibody
    • Voltage-gated sodium channel subunit alpha Nav1.3 antibody
    • Voltage-gated sodium channel subunit alpha Nav1.4 antibody
    • Voltage-gated sodium channel subunit alpha Nav1.5 antibody
    • Voltage-gated sodium channel subunit alpha Nav1.6 antibody
    • Voltage-gated sodium channel subunit alpha Nav1.7 antibody
    • Voltage-gated sodium channel subunit alpha Nav1.8 antibody
    • Voltage-gated sodium channel subunit alpha Nav1.9 antibody
    see all

Anti-pan Sodium Channel antibody 图像

  • All lanes : Anti-pan Sodium Channel antibody (ab53724) at 1/500 dilution

    Lane 1 : extracts from HuvEc cells
    Lane 2 : extracts from HuvEc cells with immunizing peptide


    Predicted band size : 227 kDa
    Observed band size : 227 kDa

Anti-pan Sodium Channel antibody (ab53724)参考文献

ab53724 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab53724.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"