Anti-pan Cytokeratin抗体[PCK-26] (FITC) (ab11214)

概述

  • 产品名称Anti-pan Cytokeratin抗体[PCK-26] (FITC)
    参阅全部 pan Cytokeratin 一抗
  • 描述
    小鼠单克隆抗体[PCK-26] to pan Cytokeratin (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 经测试应用适用于: ICC/IF, IHC-Pmore details
  • 种属反应性
    ab11214 reacts with cytokeratins from many species (e.g., rabbit, guinea pig, goat, bovine, sheep, rat, mouse, hamster, dog, cat, chicken, viper, lizard and carp).
  • 免疫原

    Cytokeratin preparation from human epidermis.

性能

应用

Our Abpromise guarantee covers the use of ab11214 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration.
IHC-P 1/25 - 1/50.

靶标

  • 相关性Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 1, 4, 5, 6, and 8 are members of the type II neutral to basic subfamily. Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin (mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues. It facilitates typing of normal, metaplastic and neoplastic cells. Synergy between the various components results in staining amplification. This enables identification of cells, which would otherwise be stained only marginally. The mixture may aid in the discrimination of carcinomas and nonepithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micrometastases in lymph nodes, bone marrow and other tissues and for determining the origin of poorly differentiated tumors. There are two types of cytokeratins the acidic type I cytokeratins and the basic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Usually the type II cytokeratins are 8kD larger than their type I counterparts.
  • 细胞定位Cytoplasmic

Anti-pan Cytokeratin antibody [PCK-26] (FITC) (ab11214)参考文献

ab11214 has not yet been referenced specifically in any publications.

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The antibodies ab6401 and ab11214 are from the same clone [PCK-26], so they are the same antibody with similar binding characteristics. The difference is that ab6401 is not purified and is not conjugated while ab11...

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Thank you for your enquiry and I'm sorry to hear that you are experiencing difficulty with ab11214 and ab11212. What lot numbers did you receive (the lot number is located on the vials)? What was the Abcam order number or purchase order number that was...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"