pan Caspase (active) Red Staining试剂盒(ab65616)

概述

  • 产品名称pan Caspase (active) Red Staining试剂盒
    参阅全部 Caspase 试剂盒
  • 测试
    100 x 1 assay
  • 样品类型
    Adherent cells, Suspension cells
  • 检测类型Enzyme activity
  • 检测时间
    2h 00m
  • 产品概述

    Abcam's pan Caspase (active) Red Staining Kit provides a convenient means for detecting activated caspases in living cells. The assay utilizes the caspase family inhibitor VAD-FMK conjugated to sulfo-rhodamine (Red-VAD-FMK) as the fluorescent in situ marker. Red-VAD-FMK is cell permeable, nontoxic, and irreversibly binds to activated caspases in apoptotic cells.
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  • 说明

    Activation of caspases plays a central role in apoptosis.

  • 经测试应用适用于: FM, Flow Cyt, Functional Studiesmore details

性能

  • 相关性Caspases are members of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.
  • 细胞定位Cytoplasmic

应用

Our Abpromise guarantee covers the use of ab65616 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
FM Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent dilution.
Functional Studies Use at an assay dependent dilution.

实验方案

pan Caspase (active) Red Staining Kit (ab65616)参考文献

ab65616 has not yet been referenced specifically in any publications.

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