概述

  • 产品名称Anti-PAM抗体
    参阅全部 PAM 一抗
  • 描述
    兔多克隆抗体to PAM
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 146-195 (PKGVGFRVGG ETGSKYFVLQ VHYGDISAFR DNNKDCSGVS LHLTRLPQPL) of Human PAM (NP_000910).

  • 阳性对照
    • 721_B cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab105069 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 108 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.
  • 序列相似性In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
    In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
    Contains 5 NHL repeats.
  • 细胞定位Membrane and Secreted. Secreted from secretory granules.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AMD_HUMAN antibody
    • PAL antibody
    • PAM antibody
    • Pancreatic peptidylglycine alpha amidating monooxygenase antibody
    • Peptidyl alpha amidating enzyme antibody
    • Peptidyl alpha hydroxyglycine alpha amidating lyase antibody
    • Peptidyl-alpha-hydroxyglycine alpha-amidating lyase antibody
    • Peptidylamidoglycolate lyase antibody
    • Peptidylglycine 2 hydroxylase antibody
    • Peptidylglycine alpha amidating monooxygenase antibody
    • Peptidylglycine alpha hydroxylating monooxygenase antibody
    • PHM antibody
    see all

Anti-PAM antibody 图像

  • Anti-PAM antibody (ab105069) at 1 µg/ml + 721_B cell lysate at 10 µg

    Predicted band size : 108 kDa

Anti-PAM antibody (ab105069)参考文献

ab105069 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab105069.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"