概述

  • 产品名称Anti-PAK5抗体
    参阅全部 PAK5 一抗
  • 描述
    兔多克隆抗体to PAK5
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide from the C terminal region of Human PAK5.

  • 阳性对照
    • Human brain tissue; Rat brain cells extracts

性能

应用

Our Abpromise guarantee covers the use of ab110069 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 81 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能The activated kinase acts on a variety of targets.
  • 组织特异性Predominantly expressed in brain.
  • 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 CRIB domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Autophosphorylated when activated by CDC42/p21.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EC 2.7.11.1 antibody
    • KIAA1264 antibody
    • MGC26232 antibody
    • p21 activated kinase 7 antibody
    • p21 protein (Cdc42/Rac)-activated kinase 7 antibody
    • p21(CDKN1A) activated kinase 7 antibody
    • p21-activated kinase 5 antibody
    • p21-activated kinase 7 antibody
    • PAK 5 antibody
    • PAK 7 antibody
    • PAK-5 antibody
    • PAK-7 antibody
    • PAK5 antibody
    • PAK7 antibody
    • PAK7_HUMAN antibody
    • Protein kinase PAK5 antibody
    • Serine/threonine protein kinase PAK 7 antibody
    • Serine/threonine-protein kinase PAK 7 antibody
    see all

Anti-PAK5 antibody 图像

  • All lanes : Anti-PAK5 antibody (ab110069) at 1/500 dilution

    Lane 1 : extracts from Rat brain cells
    Lane 2 : extracts from Rat brain cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 81 kDa
  • Immunohistochemical analysis of paraffin embedded Human brain tissue, using a 1/50 dilution of ab110069 with (right) or without (left) the immunizing peptide.

Anti-PAK5 antibody (ab110069)参考文献

This product has been referenced in:
  • Fang ZP  et al. P21-activated kinase 5 plays essential roles in the proliferation and tumorigenicity of human hepatocellular carcinoma. Acta Pharmacol Sin N/A:N/A (2013). Read more (PubMed: 23685956) »

See 1 Publication for this product

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