概述

  • 产品名称
  • 描述
    兔多克隆抗体to PAK5
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide from the C terminal region of Human PAK5.

  • 阳性对照
    • Human brain tissue; Rat brain cells extracts

性能

应用

Our Abpromise guarantee covers the use of ab110069 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 81 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    The activated kinase acts on a variety of targets.
  • 组织特异性
    Predominantly expressed in brain.
  • 序列相似性
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 CRIB domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰
    Autophosphorylated when activated by CDC42/p21.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EC 2.7.11.1 antibody
    • KIAA1264 antibody
    • MGC26232 antibody
    • p21 activated kinase 7 antibody
    • p21 protein (Cdc42/Rac)-activated kinase 7 antibody
    • p21(CDKN1A) activated kinase 7 antibody
    • p21-activated kinase 5 antibody
    • p21-activated kinase 7 antibody
    • PAK 5 antibody
    • PAK 7 antibody
    • PAK-5 antibody
    • PAK-7 antibody
    • PAK5 antibody
    • PAK7 antibody
    • PAK7_HUMAN antibody
    • Protein kinase PAK5 antibody
    • Serine/threonine protein kinase PAK 7 antibody
    • Serine/threonine-protein kinase PAK 7 antibody
    see all

图片

  • All lanes : Anti-PAK5 antibody (ab110069) at 1/500 dilution

    Lane 1 : extracts from Rat brain cells
    Lane 2 : extracts from Rat brain cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 81 kDa
  • Immunohistochemical analysis of paraffin embedded Human brain tissue, using a 1/50 dilution of ab110069 with (right) or without (left) the immunizing peptide.

文献

This product has been referenced in:
  • Aburatani T  et al. High expression of P21-activated kinase 5 protein is associated with poor survival in gastric cancer. Oncol Lett 14:404-410 (2017). Read more (PubMed: 28693183) »
  • Gu X  et al. Efficient inhibition of human glioma development by RNA interference-mediated silencing of PAK5. Int J Biol Sci 11:230-7 (2015). WB, IHC . Read more (PubMed: 25632266) »

See all 4 Publications for this product

客户评价及客户问答

There are currently no Customer reviews or Questions for ab110069.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册