概述

  • 产品名称Anti-PAK3抗体
    参阅全部 PAK3 一抗
  • 描述
    小鼠单克隆抗体to PAK3
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant fragment: MSDGLDNEEK PPAPPLRMNS NNRDSSALNH SSKPLPMAPE EKNKKARLRS IFPGGGDKTN KKKEKERPEI SLPSDFEHTI HVGFDAVTGE , corresponding to amino acids 1-90 of Human PAK3

性能

应用

Our Abpromise guarantee covers the use of ab58281 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 62 kDa.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 相关性PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. PAK3 forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. It may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. A point mutation in this gene has been linked to nonsyndromic X-linked mental retardation.
  • 细胞定位Cytoplasmic
  • 数据库链接
  • 别名
    • Beta PAK antibody
    • bPAK antibody
    • CDKN1A antibody
    • hPAK3 antibody
    • Mental retardation X linked 30 antibody
    • MRX30 antibody
    • MRX47 antibody
    • Oligophrenin 3 antibody
    • OPHN3 antibody
    • p21 (CDKN1A) activated kinase 3 antibody
    • p21 activated kinase 3 antibody
    • p21 CDKN1A activated kinase 3 antibody
    • P21 protein (Cdc42/Rac) activated kinase 3 antibody
    • PAK-3 antibody
    • PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 antibody
    • PAK3beta antibody
    • Pak65alpha antibody
    • Pak65beta antibody
    • Serine threonine protein kinase PAK 3 antibody
    • Stk4 antibody
    see all

Anti-PAK3 antibody 图像



  • Predicted band size : 62 kDa
    PAK3 antibody (ab58281) at 1ug/lane + NIH/3T3 cell lysate at 25ug/lane.
  • ab58281 at 10 ug/ml staining PAK3 in mouse NIH/3T3 cells by Immunocytochemistry/ Immunofluorescence.

Anti-PAK3 antibody (ab58281)参考文献

ab58281 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"