Anti-PAK1 (phospho S204)抗体(ab79503)


  • 产品名称
    Anti-PAK1 (phospho S204)抗体
    参阅全部 PAK1 一抗
  • 描述
    兔多克隆抗体to PAK1 (phospho S204)
  • 特异性
    ab79503 detects endogenous levels of PAK1 only when phosphorylated at serine 204.
  • 经测试应用
    适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic phosphopeptide derived from human PAK1 around the phosphorylation site of serine 204 (TRSPVI)

  • 阳性对照
    • IHC: human brain tissue WB: extracts from 3T3 cells (treated with UV for 15mins)



Our Abpromise guarantee covers the use of ab79503 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 61 kDa.
ELISA 1/5000.
IHC-P 1/50 - 1/100.


  • 功能
    The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
  • 序列相似性
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 CRIB domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰
    Autophosphorylated when activated by CDC42/p21 and RAC1.
  • 细胞定位
    Cytoplasm. Cell junction > focal adhesion. Recruited to focal adhesions upon activation.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ADRB2 antibody
    • Alpha PAK antibody
    • Alpha-PAK antibody
    • MGC130000 antibody
    • MGC130001 antibody
    • p21 activated kinase 1 antibody
    • p21 protein (Cdc42/Rac) activated kinase 1 antibody
    • p21-activated kinase 1 antibody
    • p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related) antibody
    • p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) antibody
    • p65 PAK antibody
    • p65-PAK antibody
    • P68-PAK antibody
    • PAK alpha antibody
    • PAK-1 antibody
    • Pak1 antibody
    • PAK1_HUMAN antibody
    • Paka antibody
    • PAKalpha antibody
    • Protein kinase MUK2 antibody
    • Rac/p21-activated kinase antibody
    • Serine/threonine-protein kinase PAK 1 antibody
    • STE20 homolog yeast antibody
    see all

Anti-PAK1 (phospho S204) antibody 图像

  • All lanes : Anti-PAK1 (phospho S204) antibody (ab79503) at 1/1000 dilution

    Lane 1 : extracts from 3T3 cells (treated with UV for 15 mins)
    Lane 2 : extracts from 3T3 cells (treated with UV for 15 mins) with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 61 kDa
    Observed band size : 61 kDa
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, stained with ab79503, at 1/100 dilution, in the absence and presence of the immunising peptide

Anti-PAK1 (phospho S204) antibody (ab79503)参考文献

ab79503 has not yet been referenced specifically in any publications.

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