概述

  • 产品名称Anti-PAIP1抗体
    参阅全部 PAIP1 一抗
  • 描述
    兔多克隆抗体to PAIP1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MSDGFDRAPE QTRPLRAPPS SQDKIPQQNS ESAMAKPQVV VAPVLMSKLS) of Human PAIP1 (NP_877590).

  • 阳性对照
    • Human fetal heart cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab106325 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
  • 序列相似性Contains 1 MIF4G domain.
  • 结构域Only the PABPC1-interacting motif-1 (PAM1) stimulates translation initiation.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MGC12360 antibody
    • OTTHUMP00000221601 antibody
    • OTTMUSP00000026880 antibody
    • PABC1 interacting protein 1 antibody
    • PABP interacting protein 1 antibody
    • PABP-interacting protein 1 antibody
    • PAIP 1 antibody
    • PAIP-1 antibody
    • Paip1 antibody
    • PAIP1_HUMAN antibody
    • Poly(A) binding protein interacting protein 1 antibody
    • Poly(A)-binding protein-interacting protein 1 antibody
    • Polyadenylate binding protein interacting protein 1 antibody
    • Polyadenylate-binding protein-interacting protein 1 antibody
    see all

Anti-PAIP1 antibody 图像

  • Anti-PAIP1 antibody (ab106325) at 0.5 µg/ml + Human fetal heart cell lysate at 10 µg

    Predicted band size : 54 kDa

Anti-PAIP1 antibody (ab106325)参考文献

ab106325 has not yet been referenced specifically in any publications.

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