概述

  • 产品名称Anti-PAF49抗体
    参阅全部 PAF49 一抗
  • 描述
    兔多克隆抗体to PAF49
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 404-454 of Human PAF49.

性能

应用

Our Abpromise guarantee covers the use of ab92428 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
ICC/IF
  • 应用说明ICC/IF: Use at an assay dependent dilution.
    IHC-P: 1/100 - 1/1500.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation.
      Isoform 2 has been described as a component of preformed T-cell receptor (TCR) complex.
    • 序列相似性Belongs to the eukaryotic RPA34 RNA polymerase subunit family.
    • 翻译后修饰Isoform 2 undergoes tyrosine phosphorylation upon T-cell receptor (TCR) stimulation. This phosphorylation has not been confirmed by other group.
      Isoform 1 is phosphorylated on tyrosine residues in initiation-competent Pol I-beta complexes but not in Pol I-alpha complexes.
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Nucleus > nucleolus. Chromosome. Found at the fibrillar centers of the nucleolus in interphase and during cell division it is localized to the nucleolus organizer regions of the chromosomes.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A34.5 antibody
      • Anti sense to ERCC 1 protein antibody
      • Antisense to ERCC-1 protein antibody
      • ASE 1 antibody
      • ASE-1 antibody
      • ASE1 antibody
      • CAST antibody
      • CD3 epsilon associated protein antibody
      • CD3-epsilon-associated protein antibody
      • CD3E antigen, epsilon polypeptide associated protein antibody
      • CD3E associated protein antibody
      • CD3e molecule, epsilon associated protein antibody
      • CD3E-associated protein antibody
      • CD3EAP antibody
      • DNA directed RNA polymerase I subunit RPA34 antibody
      • DNA-directed RNA polymerase I subunit RPA34 antibody
      • MGC118851 antibody
      • PAF 49 antibody
      • RNA polymerase I associated factor PAF49 antibody
      • RNA polymerase I-associated factor PAF49 antibody
      • RPA34_HUMAN antibody
      see all

    Anti-PAF49 antibody 图像

    • Formaldehyde fixed asynchronous HeLa cells detected with ab92428 at 1/250 dilution

    Anti-PAF49 antibody (ab92428)参考文献

    ab92428 has not yet been referenced specifically in any publications.

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