Anti-PACAP receptor抗体(ab28670)

概述

  • 产品名称Anti-PACAP receptor抗体
    参阅全部 PACAP receptor 一抗
  • 描述
    兔多克隆抗体to PACAP receptor
  • 经测试应用适用于: IHC-P, ICC, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide:

    LSKSSSQIRMSGLPADNLAT

    conjugated to KLH, corresponding to amino acids 506-525 of Human PACAP receptor.

性能

应用

Our Abpromise guarantee covers the use of ab28670 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/500.
ICC 1/1000.
WB 1/1000. Detects a band of approximately 40-60 kDa (predicted molecular weight: 55 kDa).

靶标

  • 功能This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
  • 组织特异性Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.
  • 序列相似性Belongs to the G-protein coupled receptor 2 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ADCYAP1 R1 antibody
    • ADCYAP1R 1 antibody
    • ADCYAP1R1 antibody
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1 antibody
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I antibody
    • PAC 1 antibody
    • PAC1 antibody
    • PAC1R antibody
    • PACAP receptor 1 antibody
    • PACAP type I receptor antibody
    • PACAP-R-1 antibody
    • PACAP-R1 antibody
    • PACAP1 R antibody
    • PACAPR antibody
    • PACAPRI antibody
    • PACR_HUMAN antibody
    • Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop antibody
    • Pituitary adenylate cyclase activating polypeptide receptor antibody
    • Pituitary adenylate cyclase activating polypeptide type I receptor precursor antibody
    • Pituitary adenylate cyclase-activating polypeptide 1, receptor for antibody
    • Pituitary adenylate cyclase-activating polypeptide type I receptor antibody
    • pvr1 antibody
    see all

Anti-PACAP receptor antibody 图像

  • ab28670 staining Human PACAP receptor in human myenteric ganglia cells of the small intestine by immunohistochemistry using paraffin embedded tissue.

Anti-PACAP receptor antibody (ab28670)参考文献

This product has been referenced in:
  • Ortner A  et al. VPAC receptor mediated tumor cell targeting by protamine based nanoparticles. J Drug Target 18:457-67 (2010). ICC ; Human . Read more (PubMed: 20050817) »

See 1 Publication for this product

Product Wall

Application Western blot
Loading amount 25 µg
Gel Running Conditions Reduced Denaturing (10% Gel)
Sample Mouse Tissue lysate - whole (Dorsal Hippocampal Tissue)
Specification Dorsal Hippocampal Tissue
Blocking step I-Block as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 0.2% · Temperature: 20°C
Username

Abcam user community

Verified customer

提交于 Oct 14 2013

Thank you for your reply.

Because ab8901 has been validated for use in rat and RIA, it will be guaranteed for your experiments and would not qualify for the testing discount program. I would be happy to manually submit your Abreview and award...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"