概述

  • 产品名称
  • 描述
    兔多克隆抗体to PAAF1
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, between N-terminal amino acids 115-145 of Human PAAF1.

  • 阳性对照
    • A549 cell lysate and Human brain tissue

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG

应用

Our Abpromise guarantee covers the use of ab103566 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 42 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
  • 组织特异性
    Ubiquitously expressed, with highest levels in kidney, brain and testis.
  • 序列相似性
    Belongs to the WD repeat PAAF1/RPN14 family.
    Contains 5 WD repeats.
  • Information by UniProt
  • 数据库链接
  • 别名
    • PAAF antibody
    • PAAF1 antibody
    • PAAF1_HUMAN antibody
    • Proteasomal ATPase-associated factor 1 antibody
    • Protein G-16 antibody
    • Rpn14 antibody
    • WD repeat domain 71 antibody
    • WD repeat-containing protein 71 antibody
    • WDR71 antibody
    see all

图片

  • Anti-PAAF1 antibody (ab103566) at 1/100 dilution + A549 cell lysate at 35 µg

    Predicted band size : 42 kDa
  • IHC analysis in formalin fixed and paraffin embedded Human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining, using ab103566 at a dilution of 1/50.

文献

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