Anti-p8/NUPR1抗体(ab234696)
Key features and details
- Rabbit polyclonal to p8/NUPR1
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-p8/NUPR1抗体
参阅全部 p8/NUPR1 一抗 -
描述
兔多克隆抗体to p8/NUPR1 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment corresponding to Human p8/NUPR1 aa 2-64.
Database link: O60356 -
阳性对照
- IHC-P: Human pancreatic tissue. ICC/IF: PC-3 cells.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
纯度
Protein G purified -
纯化说明
Purity >95%. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
-
Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab234696于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
1/20 - 1/200.
|
|
ICC/IF |
1/50 - 1/200.
|
说明 |
---|
IHC-P
1/20 - 1/200. |
ICC/IF
1/50 - 1/200. |
靶标
-
功能
Could participate in the response to proapoptotic stimuli and promotes cellular growth in a way that helps the tissue counteract diverse injuries. May contribute to the metastatic phenotype. -
组织特异性
Highly expressed in pancreas. -
翻译后修饰
Phosphorylated. -
细胞定位
Nucleus. - Information by UniProt
-
数据库链接
- Entrez Gene: 26471 Human
- SwissProt: O60356 Human
- Unigene: 513463 Human
-
别名
- Candidate of metastasis 1 antibody
- COM1 antibody
- Nuclear protein 1 antibody
see all
图片
-
Paraffin-embedded human pancreatic tissue stained for p8/NUPR1 using ab234696 at 1/100 dilution in immunohistochemical analysis.
-
PC-3 (human prostate adenocarcinoma cell line) cells stained for p8/NUPR1 (green) using ab234696 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® congugated Goat Anti-Rabbit IgG (H+L).
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (3)
ab234696 被引用在 3 文献中.
- Sauler M et al. Characterization of the COPD alveolar niche using single-cell RNA sequencing. Nat Commun 13:494 (2022). PubMed: 35078977
- Zhan Y et al. NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma. BMC Med 20:365 (2022). PubMed: 36258210
- He W et al. NUPR1 is a novel potential biomarker and confers resistance to sorafenib in clear cell renal cell carcinoma by increasing stemness and targeting the PTEN/AKT/mTOR pathway. Aging (Albany NY) 13:14015-14038 (2021). PubMed: 34030133