Anti-p75 NGF Receptor抗体[NGFR5] - BSA and Azide free (ab212682)
Key features and details
- Mouse monoclonal [NGFR5] to p75 NGF Receptor - BSA and Azide free
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
Anti-p75 NGF Receptor抗体[NGFR5] - BSA and Azide free
参阅全部 p75 NGF Receptor 一抗 -
描述
小鼠单克隆抗体[NGFR5] to p75 NGF Receptor - BSA and Azide free -
宿主
Mouse -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
不与反应: Mouse, Rat -
免疫原
Tissue, cells or virus corresponding to Human p75 NGF Receptor. Immunogen from p75 NGF Receptor from A875 melanoma cells.
Database link: P08138 -
表位
Epitope spans aa 1-160 of the extracellular domain of NGFR/NTR. -
阳性对照
- Neuronal axons, Schwann cells, and perineural cells of peripheral nerves, or tumors of nerve sheath differentiation e.g. Schwannoma, Neurofibroma. Soma and axons of sensory neurons, and ganglionic satellite cells. Melanomas.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.2
Constituent: 100% PBS -
无载体
是 -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
Purified from bioreactor concentrate. -
克隆
单克隆 -
克隆编号
NGFR5 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Compatible Secondaries
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Conjugation kits
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab212682于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
for 30 minutes at room temperature. |
说明 |
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IHC-P
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. for 30 minutes at room temperature. |
靶标
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功能
Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. -
序列相似性
Contains 1 death domain.
Contains 4 TNFR-Cys repeats. -
结构域
Death domain is responsible for interaction with RANBP9.
The extracellular domain is responsible for interaction with NTRK1. -
翻译后修饰
N- and O-glycosylated.
O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc.
Phosphorylated on serine residues. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 4804 Human
- Omim: 162010 Human
- SwissProt: P08138 Human
- Unigene: 415768 Human
- Unigene: 681726 Human
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别名
- CD271 antibody
- CD271 antigen antibody
- Gp80 LNGFR antibody
see all
图片
数据表及文件
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Datasheet download
文献 (0)
ab212682 尚未被引用在任何文献中。